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Sequential Steps in Human Immunodeficiency Virus Particle Maturation Revealed by Alterations of Individual Gag Polyprotein Cleavage Sites

Retroviruses are produced as immature particles containing structural polyproteins, which are subsequently cleaved by the viral proteinase (PR). Extracellular maturation leads to condensation of the spherical core to a capsid shell formed by the capsid (CA) protein, which encases the genomic RNA com...

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Autors principals: Wiegers, Klaus, Rutter, Gabriel, Kottler, Hubert, Tessmer, Uwe, Hohenberg, Heinz, Kräusslich, Hans-Georg
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC109729/
https://ncbi.nlm.nih.gov/pubmed/9525604
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