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Sequential Steps in Human Immunodeficiency Virus Particle Maturation Revealed by Alterations of Individual Gag Polyprotein Cleavage Sites

Retroviruses are produced as immature particles containing structural polyproteins, which are subsequently cleaved by the viral proteinase (PR). Extracellular maturation leads to condensation of the spherical core to a capsid shell formed by the capsid (CA) protein, which encases the genomic RNA com...

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Main Authors: Wiegers, Klaus, Rutter, Gabriel, Kottler, Hubert, Tessmer, Uwe, Hohenberg, Heinz, Kräusslich, Hans-Georg
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC109729/
https://ncbi.nlm.nih.gov/pubmed/9525604
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