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Imaging the Extracellular pH of Tumors by MRI after Injection of a Single Cocktail of T(1) and T(2) Contrast Agents
The extracellular pH (pH(e)) of solid tumors is acidic, and there is evidence that acidic pH(e) is related to invasiveness. Herein, we describe an MRI single infusion method (SIM) to measure pH(e) in gliomas using a cocktail of contrast agents (CA). The cocktail contained Gd-DOTA-4AmP and Dy-DOTP, w...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3693774/ https://ncbi.nlm.nih.gov/pubmed/21604311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1701 |
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