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Improved pH measurements with a single PARACEST MRI contrast agent

The measurement of extracellular pH has potential utility for assessing the therapeutic effects of pH-dependent and pH-altering therapies. A PARAmagnetic chemical exchange saturation transfer (PARACEST) MRI contrast agent, Yb–DO3A–oAA, has two CEST effects that are dependent on pH. A ratio derived f...

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Detalhes bibliográficos
Publicado no:Contrast Media Mol Imaging
Main Authors: Sheth, Vipul R., Liu, Guanshu, Li, Yuguo, Pagel, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882612/
https://ncbi.nlm.nih.gov/pubmed/22344877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmmi.460
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