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An extracellular MRI polymeric contrast agent that degrades at physiological pH

Macromolecular contrast agents have the potential to assist magnetic resonance imaging (MRI) due to their high relaxivity, but are not clinically useful because of toxicity due to poor clearance. We have prepared a biodegradable ketal-based polymer contrast agent which is designed to degrade rapidly...

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Detalhes bibliográficos
Main Authors: Schopf, Eric, Sankaranarayanan, Jagadis, Chan, Minnie, Mattrey, Robert, Almutairi, Adah
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443308/
https://ncbi.nlm.nih.gov/pubmed/22657107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp2005998
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