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An extracellular MRI polymeric contrast agent that degrades at physiological pH

Macromolecular contrast agents have the potential to assist magnetic resonance imaging (MRI) due to their high relaxivity, but are not clinically useful because of toxicity due to poor clearance. We have prepared a biodegradable ketal-based polymer contrast agent which is designed to degrade rapidly...

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Détails bibliographiques
Auteurs principaux: Schopf, Eric, Sankaranarayanan, Jagadis, Chan, Minnie, Mattrey, Robert, Almutairi, Adah
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443308/
https://ncbi.nlm.nih.gov/pubmed/22657107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp2005998
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