Role for CCR5Δ32 Protein in Resistance to R5, R5X4, and X4 Human Immunodeficiency Virus Type 1 in Primary CD4(+) Cells

CCR5Δ32 is a loss-of-function mutation that abolishes cell surface expression of the human immunodeficiency virus (HIV) coreceptor CCR5 and provides genetic resistance to HIV infection and disease progression. Since CXCR4 and other HIV coreceptors also exist, we hypothesized that CCR5Δ32-mediated re...

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Autori principali: Agrawal, Lokesh, Lu, Xihua, Qingwen, Jin, VanHorn-Ali, Zainab, Nicolescu, Ioan Vlad, McDermott, David H., Murphy, Philip M., Alkhatib, Ghalib
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC369216/
https://ncbi.nlm.nih.gov/pubmed/14963124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.5.2277-2287.2004
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