CCR5Δ32 Protein Expression and Stability Are Critical for Resistance to Human Immunodeficiency Virus Type 1 In Vivo

Human immunodeficiency virus type 1 (HIV-1) infection of individuals carrying the two alleles of the CCR5Δ32 mutation (CCR5(−/−)) has rarely been reported, but how the virus overcomes the CCR5Δ32 protective effect in these cases has not been delineated. We have investigated this in 6 infected (HIV(+...

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Main Authors: Agrawal, Lokesh, Jin, Qingwen, Altenburg, Jeff, Meyer, L., Tubiana, R., Theodorou, Ioannis, Alkhatib, Ghalib
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951285/
https://ncbi.nlm.nih.gov/pubmed/17522201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00068-07
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