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CCR5Δ32 59537-G/A Promoter Polymorphism Is Associated with Low Translational Efficiency and the Loss of CCR5Δ32 Protective Effects

We have recently demonstrated that the CCR5Δ32 protein interacts with CCR5 and CXCR4 and down-modulates their cell surface expression. We have also reported the absence of detectable expression of the truncated CCR5Δ32 protein in four out of six human immunodeficiency virus-infected (HIV(+)) CCR5(−/...

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Detalhes bibliográficos
Main Authors: Jin, Qingwen, Agrawal, Lokesh, Meyer, L., Tubiana, R., Theodorou, Ioannis, Alkhatib, Ghalib
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258923/
https://ncbi.nlm.nih.gov/pubmed/18094161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01596-07
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