Role for CCR5Δ32 Protein in Resistance to R5, R5X4, and X4 Human Immunodeficiency Virus Type 1 in Primary CD4(+) Cells

CCR5Δ32 is a loss-of-function mutation that abolishes cell surface expression of the human immunodeficiency virus (HIV) coreceptor CCR5 and provides genetic resistance to HIV infection and disease progression. Since CXCR4 and other HIV coreceptors also exist, we hypothesized that CCR5Δ32-mediated re...

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Autores principales: Agrawal, Lokesh, Lu, Xihua, Qingwen, Jin, VanHorn-Ali, Zainab, Nicolescu, Ioan Vlad, McDermott, David H., Murphy, Philip M., Alkhatib, Ghalib
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC369216/
https://ncbi.nlm.nih.gov/pubmed/14963124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.5.2277-2287.2004
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