Role for CCR5Δ32 Protein in Resistance to R5, R5X4, and X4 Human Immunodeficiency Virus Type 1 in Primary CD4(+) Cells

CCR5Δ32 is a loss-of-function mutation that abolishes cell surface expression of the human immunodeficiency virus (HIV) coreceptor CCR5 and provides genetic resistance to HIV infection and disease progression. Since CXCR4 and other HIV coreceptors also exist, we hypothesized that CCR5Δ32-mediated re...

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Detalhes bibliográficos
Main Authors: Agrawal, Lokesh, Lu, Xihua, Qingwen, Jin, VanHorn-Ali, Zainab, Nicolescu, Ioan Vlad, McDermott, David H., Murphy, Philip M., Alkhatib, Ghalib
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369216/
https://ncbi.nlm.nih.gov/pubmed/14963124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.5.2277-2287.2004
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