Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set

BACKGROUND: Somatic cell nuclear transfer (SCNT) using genetically engineered donor cells is currently the most widely used strategy to generate tailored pig models for biomedical research. Although this approach facilitates a similar spectrum of genetic modifications as in rodent models, the outcom...

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Main Authors: Kurome, Mayuko, Geistlinger, Ludwig, Kessler, Barbara, Zakhartchenko, Valeri, Klymiuk, Nikolai, Wuensch, Annegret, Richter, Anne, Baehr, Andrea, Kraehe, Katrin, Burkhardt, Katinka, Flisikowski, Krzysztof, Flisikowska, Tatiana, Merkl, Claudia, Landmann, Martina, Durkovic, Marina, Tschukes, Alexander, Kraner, Simone, Schindelhauer, Dirk, Petri, Tobias, Kind, Alexander, Nagashima, Hiroshi, Schnieke, Angelika, Zimmer, Ralf, Wolf, Eckhard
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691671/
https://ncbi.nlm.nih.gov/pubmed/23688045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-43
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