Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products.
The v-abl transforming protein P160v-abl and the P210c-abl gene product of the translocated c-abl gene in Philadelphia chromosome-positive chronic myelogenous leukemia cells have tyrosine-specific protein kinase activity. Under similar assay conditions the normal c-abl gene products, murine P150c-ab...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1985
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369126/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3879812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.11.3116-3123.1985 |
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