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Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products.

The v-abl transforming protein P160v-abl and the P210c-abl gene product of the translocated c-abl gene in Philadelphia chromosome-positive chronic myelogenous leukemia cells have tyrosine-specific protein kinase activity. Under similar assay conditions the normal c-abl gene products, murine P150c-ab...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Mol Cell Biol
Príomhchruthaitheoirí: Konopka, J B, Witte, O N
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Taylor & Francis 1985
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3879812/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.11.3116-3123.1985
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