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RB1, development, and cancer

The RB1 gene is the first tumor suppressor gene identified whose mutational inactivation is the cause of a human cancer, the pediatric cancer retinoblastoma. The twenty five years of research since its discovery has not only illuminated a general role for RB1 in human cancer, but also its critical i...

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Detalhes bibliográficos
Main Authors: Chinnam, Meenalakshmi, Goodrich, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691055/
https://ncbi.nlm.nih.gov/pubmed/21295686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-380916-2.00005-X
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