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RB1, development, and cancer
The RB1 gene is the first tumor suppressor gene identified whose mutational inactivation is the cause of a human cancer, the pediatric cancer retinoblastoma. The twenty five years of research since its discovery has not only illuminated a general role for RB1 in human cancer, but also its critical i...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3691055/ https://ncbi.nlm.nih.gov/pubmed/21295686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-380916-2.00005-X |
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