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Cell cycle and beyond: Exploiting new RB1 controlled mechanisms for cancer therapy
Recent studies highlight the importance of the RB1 tumor suppressor as a target for cancer therapy. Canonically, RB1 regulates cell cycle progression and represents the down-stream target for CDK4/6 inhibitors that are in clinical use. However, newly discovered features of the RB1-pathway suggest ne...
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| Publicado no: | Trends Cancer |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719339/ https://ncbi.nlm.nih.gov/pubmed/31174843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2019.03.005 |
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