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Evaluating Effects of Hypomorphic Thoc1 Alleles on Embryonic Development in Rb1 Null Mice

The Rb1 tumor suppressor protein is a molecular adaptor that physically links transcription factors like E2f with various proteins acting on DNA or RNA to repress gene expression. Loss of Rb1 liberates E2f to activate the expression of genes mediating resulting phenotypes. Most Rb1 binding proteins,...

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Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphovsmän: Chinnam, Meenalakshmi, Wang, Xiaoling, Zhang, Xiaojing, Goodrich, David W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959316/
https://ncbi.nlm.nih.gov/pubmed/27001308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01003-15
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