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Pd-catalyzed cascade carbopalladation-annulation reaction of 3-(2-iodobenzyl)-indoles into fused 6/5/7/6- and 6/5/5/6- heterocyclic systems

Polycyclic indole structures, possessing fused seven-membered rings were efficiently synthesized via the Pd-catalyzed intramolecular carbopalladation-annulation of 3-(2-iodobenzyl)-indoles and alkynes. A remarkable base effect on the chemoselectivity of this transformation has been found: switching...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chernyak, Natalia, Tilly, David, Li, Zhou, Gevorgyan, Vladimir
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690920/
https://ncbi.nlm.nih.gov/pubmed/20024323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b919991h
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