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Pd-catalyzed cascade carbopalladation-annulation reaction of 3-(2-iodobenzyl)-indoles into fused 6/5/7/6- and 6/5/5/6- heterocyclic systems

Polycyclic indole structures, possessing fused seven-membered rings were efficiently synthesized via the Pd-catalyzed intramolecular carbopalladation-annulation of 3-(2-iodobenzyl)-indoles and alkynes. A remarkable base effect on the chemoselectivity of this transformation has been found: switching...

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Detalhes bibliográficos
Main Authors: Chernyak, Natalia, Tilly, David, Li, Zhou, Gevorgyan, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690920/
https://ncbi.nlm.nih.gov/pubmed/20024323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b919991h
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