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ORGANOCOPPER-MEDIATED TWO-COMPONENT S(N)2'-SUBSTITUTION CASCADE TOWARDS N-FUSED HETEROCYCLES
Organocuprates efficiently undergo reaction with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a "double duty" in this cascade transformation, which proceeds through an S(N)2'-substitution followed by a consequent cyclois...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910007/ https://ncbi.nlm.nih.gov/pubmed/24501430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10593-012-0942-1 |
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