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ORGANOCOPPER-MEDIATED TWO-COMPONENT S(N)2'-SUBSTITUTION CASCADE TOWARDS N-FUSED HETEROCYCLES

Organocuprates efficiently undergo reaction with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a "double duty" in this cascade transformation, which proceeds through an S(N)2'-substitution followed by a consequent cyclois...

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Autori principali: Chernyak, D., Gevorgyan, V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910007/
https://ncbi.nlm.nih.gov/pubmed/24501430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10593-012-0942-1
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