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Low Temperature Organocopper-Mediated Two-Component Cross Coupling/Cycloisomerization Approach Towards N-Fused Heterocycles
Organocopper reagents smoothly react with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a “double duty” in this novel cascade transformation, which proceeds via an S(N)2’ substitution followed by a subsequent cycloisomerization step....
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615671/ https://ncbi.nlm.nih.gov/pubmed/18461954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8008705 |
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