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Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth
Tumor suppressors known to date impede cancer growth by arresting the cell cycle or promoting apoptosis. Here we show that unphosphorylated human STAT5A functions as a tumor suppressor capable of repressing multiple oncogenes via heterochromatin formation. Unphosphorylated STAT5A binds to heterochro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690839/ https://ncbi.nlm.nih.gov/pubmed/23733954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221243110 |
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