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Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer
BACKGROUND: Aberrant JAK/STAT activation has been detected in many types of human cancers. The role of JAK/STAT activation in cancer has been mostly attributed to direct transcriptional regulation of target genes by phosphorylated STAT (pSTAT), while the unphosphorylated STAT (uSTAT) is believed to...
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| Veröffentlicht in: | BMC Cancer |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7036253/ https://ncbi.nlm.nih.gov/pubmed/32087696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6649-2 |
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