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Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability
STAT (Signal transducer and activator of transcription) is a potent transcription factor and its aberrant activation by phosphorylation is associated with human cancers(1–4). We have shown previously that overactivation of JAK, which phosphorylates STAT(5,6), disrupts heterochromatin formation globa...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083919/ https://ncbi.nlm.nih.gov/pubmed/18344984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1713 |
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