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The multiple levels of regulation by p53 ubiquitination
p53 is a central integrator of a plethora of signals and outputs these signals in the form of tumor suppression. It is well accepted that ubiquitination plays a major part in p53 regulation. Nonetheless, the molecular mechanisms by which p53 activity is controlled by ubiquitination are complex. Mdm2...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690487/ https://ncbi.nlm.nih.gov/pubmed/19543236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.77 |
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