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The multiple levels of regulation by p53 ubiquitination

p53 is a central integrator of a plethora of signals and outputs these signals in the form of tumor suppression. It is well accepted that ubiquitination plays a major part in p53 regulation. Nonetheless, the molecular mechanisms by which p53 activity is controlled by ubiquitination are complex. Mdm2...

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Bibliografische gegevens
Hoofdauteurs: Lee, JT, Gu, W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690487/
https://ncbi.nlm.nih.gov/pubmed/19543236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.77
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