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p53 Ubiquitination: Mdm2 and Beyond
Although early studies have suggested that the onco-protein Mdm2 is the primary E3 ubiquitin ligase for the p53 tumor suppressor, an increasing amount of data suggests that p53 ubiquitination and degradation are more complex than once thought. The discoveries of MdmX, HAUSP, ARF, COP1, Pirh2, and AR...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3737769/ https://ncbi.nlm.nih.gov/pubmed/16455486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.01.020 |
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