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Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein

Cytoplasmic dynein is the major minus end-directed microtubule motor in eukaryotes. However, there is little structural insight into how different cargos are recognized and linked to the motor complex. Here we describe the 2.2 Å resolution crystal structure of a cargo-binding region of the dynein ad...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Yang, Salter, Hannah K., Holding, Andrew N., Johnson, Christopher M., Stephens, Elaine, Lukavsky, Peter J., Walshaw, John, Bullock, Simon L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690397/
https://ncbi.nlm.nih.gov/pubmed/23723415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.212381.112
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