The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein

Ndel1 has been implicated in a variety of dynein-related processes, but its specific function is unclear. Here we describe an experimental approach to evaluate a role of Ndel1 in dynein-dependent microtubule self-organization using Ran-mediated asters in meiotic Xenopus egg extracts. We demonstrate...

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Main Authors: Żyłkiewicz, Eliza, Kijańska, Monika, Choi, Won-Chan, Derewenda, Urszula, Derewenda, Zygmunt S., Stukenberg, P. Todd
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101096/
https://ncbi.nlm.nih.gov/pubmed/21282465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201011142
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