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Functional Dissection of LIS1 and NDEL1 Towards Understanding the Molecular Mechanisms of Cytoplasmic Dynein Regulation

LIS1 and NDEL1 are known to be essential for the activity of cytoplasmic dynein in living cells. We previously reported that LIS1 and NDEL1 directly regulated the motility of cytoplasmic dynein in an in vitro motility assay. LIS1 suppressed dynein motility and inhibited the translocation of microtub...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Torisawa, Takayuki, Nakayama, Akiko, Furuta, Ken'ya, Yamada, Masami, Hirotsune, Shinji, Toyoshima, Yoko Y.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023492/
https://ncbi.nlm.nih.gov/pubmed/21036906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169847
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