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Stress-induced CDK5 activation disrupts axonal transport via Lis1/Ndel1/dynein
Axonal transport is essential for neuronal function, and defects in transport are associated with multiple neurodegenerative diseases. Aberrant cyclin dependent kinase 5 (CDK5) activity, driven by the stress-induced activator p25, is also observed in these diseases. Here, we show that elevated CDK5...
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| Gepubliceerd in: | Cell Rep |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532378/ https://ncbi.nlm.nih.gov/pubmed/26166569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.032 |
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