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“Snapshots” of Ispinesib-induced Conformational Changes in the Mitotic Kinesin Eg5

Kinesins comprise a superfamily of molecular motors that drive a wide variety of cellular physiologies, from cytoplasmic transport to formation of the bipolar spindle in mitosis. These differing roles are reflected in corresponding polymorphisms in key kinesin structural elements. One of these is a...

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Autors principals: Kaan, Hung Yi Kristal, Major, Jennifer, Tkocz, Katarzyna, Kozielski, Frank, Rosenfeld, Steven S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689998/
https://ncbi.nlm.nih.gov/pubmed/23658017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.462648
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