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“Snapshots” of Ispinesib-induced Conformational Changes in the Mitotic Kinesin Eg5
Kinesins comprise a superfamily of molecular motors that drive a wide variety of cellular physiologies, from cytoplasmic transport to formation of the bipolar spindle in mitosis. These differing roles are reflected in corresponding polymorphisms in key kinesin structural elements. One of these is a...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689998/ https://ncbi.nlm.nih.gov/pubmed/23658017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.462648 |
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