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Structures of Mycobacterium tuberculosis FadD10 Protein Reveal a New Type of Adenylate-forming Enzyme

Mycobacterium tuberculosis has a group of 34 FadD proteins that belong to the adenylate-forming superfamily. They are classified as either fatty acyl-AMP ligases (FAALs) or fatty acyl-CoA ligases based on sequence analysis. FadD10, involved in the synthesis of a virulence-related lipopeptide, was mi...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Zhen, Ioerger, Thomas R., Wang, Feng, Sacchettini, James C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689989/
https://ncbi.nlm.nih.gov/pubmed/23625916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466912
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