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IκB Kinase β (IKKβ) Inhibits p63 Isoform γ (TAp63γ) Transcriptional Activity

Previously, we reported that IκB kinase-β(IKKβ) phosphorylates and stabilizes TAp63γ. However, the effect of this phosphorylation on TAp63γ transcriptional activity remains unclear. In this study, we showed that overexpression of IKKβ, but not its kinase dead mutant and IKKα, can surprisingly inhibi...

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Bibliografische gegevens
Hoofdauteurs: Liao, Jun-Ming, Zhang, Yu, Liao, Wenjuan, Zeng, Sheyla X., Su, Xiaohua, Flores, Elsa R., Lu, Hua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689961/
https://ncbi.nlm.nih.gov/pubmed/23589370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466540
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