IκB Kinase β (IKKβ) Inhibits p63 Isoform γ (TAp63γ) Transcriptional Activity

Previously, we reported that IκB kinase-β(IKKβ) phosphorylates and stabilizes TAp63γ. However, the effect of this phosphorylation on TAp63γ transcriptional activity remains unclear. In this study, we showed that overexpression of IKKβ, but not its kinase dead mutant and IKKα, can surprisingly inhibi...

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Autori principali: Liao, Jun-Ming, Zhang, Yu, Liao, Wenjuan, Zeng, Sheyla X., Su, Xiaohua, Flores, Elsa R., Lu, Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689961/
https://ncbi.nlm.nih.gov/pubmed/23589370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466540
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