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Age dependency of cerebral P-gp function measured with (R)-[(11)C]verapamil and PET
PURPOSE: The aim of this study was to assess the influence of age on the functional activity of the multidrug efflux transporter P-glycoprotein (P-gp) at the human blood-brain barrier. METHODS: 7 young (mean age: 27±4 years) and 6 elderly (mean age: 69±9 years) healthy volunteers underwent dynamic (...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689922/ https://ncbi.nlm.nih.gov/pubmed/19655132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-009-0709-5 |
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