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A combined accelerator mass spectrometry-positron emission tomography human microdose study with (14)C- and (11)C-labelled verapamil
BACKGROUND AND OBJECTIVE: In microdose studies, the pharmacokinetic (PK) profile of a drug in blood after administration of a dose up to 100 μg is measured with sensitive analytical techniques, such as accelerator mass spectrometry (AMS). As most drugs exert their effect in tissue rather than blood,...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763674/ https://ncbi.nlm.nih.gov/pubmed/21142292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/11537250-000000000-00000 |
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