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Proteins searching for their target on DNA by one-dimensional diffusion: overcoming the “speed-stability” paradox

The sequence dependence of DNA-protein interactions that allows proteins to find the correct reaction site also slows down the 1D diffusion of the protein along the DNA molecule, leading to the so-called “speed-stability paradox,” wherein fast diffusion along the DNA molecule is seemingly incompatib...

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Detalhes bibliográficos
Main Authors: Yu, Shi, Wang, Shihu, Larson, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689361/
https://ncbi.nlm.nih.gov/pubmed/23860925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-013-9310-3
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