The Role of High-Dimensional Diffusive Search, Stabilization, and Frustration in Protein Folding

Proteins are polymeric molecules with many degrees of conformational freedom whose internal energetic interactions are typically screened to small distances. Therefore, in the high-dimensional conformation space of a protein, the energy landscape is locally relatively flat, in contrast to low-dimens...

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Библиографические подробности
Главные авторы: Rimratchada, Supreecha, McLeish, Tom C.B., Radford, Sheena E., Paci, Emanuele
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2014
Предметы:
Proteins and Nucleic Acids
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008833/
https://ncbi.nlm.nih.gov/pubmed/24739172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.051
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