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The Role of High-Dimensional Diffusive Search, Stabilization, and Frustration in Protein Folding

Proteins are polymeric molecules with many degrees of conformational freedom whose internal energetic interactions are typically screened to small distances. Therefore, in the high-dimensional conformation space of a protein, the energy landscape is locally relatively flat, in contrast to low-dimens...

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Detalhes bibliográficos
Main Authors: Rimratchada, Supreecha, McLeish, Tom C.B., Radford, Sheena E., Paci, Emanuele
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008833/
https://ncbi.nlm.nih.gov/pubmed/24739172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.051
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