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Understanding the Role of Three-Dimensional Topology in Determining the Folding Intermediates of Group I Introns

Many RNA molecules exert their biological function only after folding to unique three-dimensional structures. For long, noncoding RNA molecules, the complexity of finding the native topology can be a major impediment to correct folding to the biologically active structure. An RNA molecule may fold t...

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Détails bibliographiques
Auteurs principaux: Chen, Chunxia, Mitra, Somdeb, Jonikas, Magdalena, Martin, Joshua, Brenowitz, Michael, Laederach, Alain
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602782/
https://ncbi.nlm.nih.gov/pubmed/23528092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.02.007
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