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Distinct contribution of electrostatics, initial conformational ensemble, and macromolecular stability in RNA folding

We distinguish the contribution of the electrostatic environment, initial conformational ensemble, and macromolecular stability on the folding mechanism of a large RNA using a combination of time-resolved “Fast Fenton” hydroxyl radical footprinting and exhaustive kinetic modeling. This integrated ap...

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Detalhes bibliográficos
Main Authors: Laederach, Alain, Shcherbakova, Inna, Jonikas, Magdalena A., Altman, Russ B., Brenowitz, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855354/
https://ncbi.nlm.nih.gov/pubmed/17438287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608765104
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