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Protein Folding in High-Dimensional Spaces: Hypergutters and the Role of Nonnative Interactions
We explore the consequences of very high dimensionality in the dynamical landscape of protein folding. Consideration of both typical range of stabilizing interactions, and folding rates themselves, leads to a model of the energy hypersurface that is characterized by the structure of diffusive “hyper...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304996/ https://ncbi.nlm.nih.gov/pubmed/15501939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.036616 |
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