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Quantifying Nonnative Interactions in the Protein-Folding Free-Energy Landscape

Protein folding is a central problem in biological physics. Energetic roughness is an important aspect that controls protein-folding stability and kinetics. The roughness is associated with conflicting interactions in the protein and is also known as frustration. Recent studies indicate that an addi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Mouro, Paulo Ricardo, de Godoi Contessoto, Vinícius, Chahine, Jorge, Junio de Oliveira, Ronaldo, Pereira Leite, Vitor Barbanti
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968343/
https://ncbi.nlm.nih.gov/pubmed/27463131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.041
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