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Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct

The epithelial sodium channel (ENaC) is one of the central effectors involved in regulation of salt and water homeostasis in the kidney. To study mechanisms of ENaC regulation, we generated knockout mice lacking the insulin receptor (InsR KO) specifically in the collecting duct principal cells. Sing...

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Autori principali: Pavlov, Tengis S., Ilatovskaya, Daria V., Levchenko, Vladislav, Li, Lijun, Ecelbarger, Carolyn M., Staruschenko, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688749/
https://ncbi.nlm.nih.gov/pubmed/23558339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-223792
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