Proteolytic Characteristics of Cathepsin D Related to the Recognition and Cleavage of Its Target Proteins

Cathepsin D (CD) plays an important role in both biological and pathological processes, although the cleavage characteristics and substrate selection of CD have yet to be fully explored. We employed liquid chromatography-tandem mass spectrometry (LC-MS/MS) to identify the CD cleavage sites in bovine...

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Main Authors: Sun, Huiying, Lou, Xiaomin, Shan, Qiang, Zhang, Ju, Zhu, Xu, Zhang, Jia, Wang, Yang, Xie, Yingying, Xu, Ningzhi, Liu, Siqi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688724/
https://ncbi.nlm.nih.gov/pubmed/23840360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065733
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