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Telomere dysfunction and Tumor Suppression-the Senescence Connection

Long lived organisms such as humans have evolved several intrinsic tumor suppressor mechanisms to combat the slew of oncogenic somatic mutations that constantly arise in proliferating stem cell compartments. One of these anti-cancer barriers is the telomere, a specialized nucleoprotein that caps the...

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Bibliografski detalji
Glavni autori: Deng, Yibin, Chan, Suzanne, Chang, Sandy
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688269/
https://ncbi.nlm.nih.gov/pubmed/18500246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2393
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