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HIV-1 Tat protein decreases dopamine transporter cell surface expression and vesicular monoamine transporter-2 function in rat striatal synaptosomes
The dopamine (DA) transporter (DAT) and vesicular monoamine transporter (VMAT2) proteins interact as a biochemical complex to regulate dopaminergic neurotransmission. We have reported that HIV-1Tat(1–86) decreases the specific [(3)H]DA uptake and [(3)H]WIN 35,428 binding sites without a change in to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3688268/ https://ncbi.nlm.nih.gov/pubmed/22570010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-012-9369-9 |
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