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In vivo knockdown of nicotinic acetylcholine receptor α1 diminishes aortic atherosclerosis
OBJECTIVE: Nicotinic acetylcholine receptor α1 (nAChRα1) was recently identified as a functional cell receptor for urokinase, a potent atherogenic molecule. Here, we test the hypothesis that nAChRα1 plays a role in the pathogenesis of atherosclerosis. METHODS: Apolipoprotein E-deficient mice were in...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3688265/ https://ncbi.nlm.nih.gov/pubmed/20810113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2010.07.057 |
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