In vivo knockdown of nicotinic acetylcholine receptor α1 diminishes aortic atherosclerosis

OBJECTIVE: Nicotinic acetylcholine receptor α1 (nAChRα1) was recently identified as a functional cell receptor for urokinase, a potent atherogenic molecule. Here, we test the hypothesis that nAChRα1 plays a role in the pathogenesis of atherosclerosis. METHODS: Apolipoprotein E-deficient mice were in...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zhang, Guoqiang, Marshall, Amanda L., Thomas, Alison L., Kernan, Kelly A., Su, Yanyuan, LeBoeuf, Renee C., Dong, Xiu Rong, Tchao, B.N. Angela
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688265/
https://ncbi.nlm.nih.gov/pubmed/20810113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2010.07.057
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares