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Iron overload diminishes atherosclerosis in apoE-deficient mice

It has been proposed that elevated levels of tissue iron increase the risk for atherosclerosis, perhaps by favoring the formation of pro-atherogenic oxidized LDL. Working with apoE-deficient (apoE(–/–)) mice, which do not require a high-fat diet to develop atherosclerosis, we compared the effects of...

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Bibliographic Details
Main Authors: Kirk, Elizabeth A., Heinecke, Jay W., LeBoeuf, Renée C.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC200187/
https://ncbi.nlm.nih.gov/pubmed/11413162
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