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A Novel Signaling Pathway: FIBROBLAST NICOTINIC RECEPTOR α1 BINDS UROKINASE AND PROMOTES RENAL FIBROSIS
The nicotinic acetylcholine receptor α1 (nAChRα1) was investigated as a potential fibrogenic molecule in the kidney, given reports that it may be an alternative urokinase (urokinase plasminogen activator; uPA) receptor in addition to the classical receptor uPAR. In a mouse obstructive uropathy model...
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Glavni autori: | , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781451/ https://ncbi.nlm.nih.gov/pubmed/19690163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.010249 |
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